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CURRICULUM VITAE |
NAME
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Jerry (Jian) Q. Feng |
| EDATAEDUCATION |
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| Undergraduate (1976) |
University of Qindao, Medical College , Qindao, China, B.S. (Medicine) |
| M.S. (Physiology,1982) |
University of Qindao, Medical College , Qindao, China, |
Ph.D. (Physiology, 1991)
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University of Connecticut, Storrs, Connecticut ,1987-1991 |
| PROFESSIONAL APPOINTMENTS |
| Professor with tenue (2007) |
Department of Biomedical Sciences |
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Baylor College of Dentistry |
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Tx A&M Health Science Center |
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3302 Gaston Avenue |
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Dallas, TX 75246 |
| Professor with tenue (2006) |
Department of Oral Biology |
| Associate Professor (1998) |
University of Missouri-Kansas City |
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Department of Oral Biology |
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University of Missouri-Kansas City |
| Assistant Professor (1996) |
Departments of Pediatric Dentistry and Medicine |
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UT Health Sciences Center at San Antonio, TX |
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Postdoctoral Fellow Departments of Physiology and Medicine |
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Medical School, University of Michigan |
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Ann Arbor, MI, 1985?1987 |
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Department of Medicine, |
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School of Medicine of UT Health Sciences Center |
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at San Antonio, TX, 1991-1995 |
| HONORS AND AWARDS |
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| 2006 |
Keynote Speaker of Annual Meeting of American Association for Dental Research at Orlando, USA |
| 2005 |
William Gies Award , International Association for Dental Research/American Association for Dental Research |
| 1998 |
Research Day Winner (Faculty Category), UT Health Sciences Center at San Antonio, TX |
| 1991 |
Excellent Research Award (Student Category), American Physiological Society, Atlanta, GE |
| PATENT |
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1. Harris, SE., Ghosh-Choudhury, N., Feng, JQ , and GR., Mundy Methods and compositions for
identifying osteogenic agents. No. 6,083,690. July, 2000 |
| 2. Feng, JQ Dmp1-Cre mice licensing to Norvarti Com. December, 2006 |
| PUBLICATIONS |
| 1. |
C. Qin, R. D’souza and JQ Feng Dentin Matrix Protein 1 (DMP1): New and Important Roles for Biomineralization and Phosphate Homeostasis J Dent Res in press |
| 2. |
Kula K, Trimmell J, Lu Y, Briscoe P and Jian Q. Feng Tooth agenesis in a family and homozygous PAX9 mutation in Exon 3: Case report World Journal of Orthodontics, accepted |
| 3. |
Baozhi Yuan, Masanori Takaiwa, Thomas L. Clemens, Jian Q. Feng, Rajiv Kumar, Peter S. Rowe, Yixia Xie, and Marc K. Drezner1 Bone is the physiologically relevant site of the PHEX/Phex mutation in X-linked hypophosphatemia JCI, in press |
| 4. |
Xu K, Y Zhang, K Ilalov, CS Carlson, Jian Q. Feng, PED. Cesare, and C-j Liu Cartilage Oligomeric Matrix Protein Associates with Granulin-Epithelin Precursor (GEP) and Potentiates GEP-stimulated Chondrocyte Proliferation J Biol Chem 282: 11347 – 11355, 2007 |
| 5. |
Lu Y, Y Xie, S Zhang, D, Vladimir, L F. Bonewald, and Jian Q. Feng DMP1 targeted Cre expression in Odontoblasts and Osteocytes. J Dent Res 86:320-325, 2007 |
| 6. |
Lu, Y, L. Ye, Y. Xie, S. Zhang, S. Yu, M. D. McKee, Y. Li, D. Eick, SL. Dallas, and JQ. Feng Rescue of Odontogenesis in Dmp1-deficient Mice by Targeted Re-expression of DMP1 Reveals Roles for DMP1 in Early Odontogenesis and Dentin Apposition in vivo Developmental Biology 303:191-201, 2007 |
| 7. |
J Zhang, He XC, Tong WG, Johnson T, Wiedemann LM, Mishina Y, Feng JQ, and L Li BMP signaling inhibits hair follicle anagen induction by restricting epithelial stem/progenitor cell activation and expansion. Stem Cells 2006; 0: 2005-0544v1 |
| 8. |
Feng JQ., L.M. Ward, S. Liu, Y. Lu, B. Yuan, X. Yu, F. Rauch, Y. Xie, S.I. Davis, S. Zhang, H. Rios, M.K. Drezner, L.F. Bonewald, L.D. Quarles and K.E. White Loss of DMP1 Causes Rickets and Osteomalacia and Identifies a Role for Osteocytes in Mineral Metabolism Nature Genetics 2006 Nov;38(11):1310-5 |
| 9. |
Zhang K, Barragan-Adjemian C, Ye L, Kotha S, Dallas M, Lu Y, Zhao S, Harris M, Harris SE, Feng JQ, Bonewald LF. E11/gp38 selective expression in osteocytes: regulation by mechanical strain and role in dendrite elongation. Mol Cell Biol. 2006 Jun;26(12):4539-52. |
| 10. |
Yongbo Lu, Shubin Zhang, Yuli Pi, Yixia Xie, and Jian Q. Feng Differential Regulation of DMP1 Expression during Odontogenesis Cells Tissues Organs 181 (3-4): 241 – 247, 2005 |
| 11. |
Rios HF, Ye L, Dusevich V, Eick D, Bonewald LF, Feng JQ DMP1 is essential for osteocyte formation and function J Musculoskelet Neuronal Interact. 5:325-7. 2005 |
| 12. |
Ling Y, Rios, H, Myers ER, Lu Y, Feng JQ, and Boskey A DMP1 Depletion Decreases Bone Mineralization In Vivo J Bone Miner Res 20 (12): 2169-77, 2005 |
| 13. |
Hector Rios, Shrinagesh V. Koushik, Haiyan Wang, Jian Wang, Hong-Ming Zhou, Andrew Lindsley, Rhonda Rogers, Zhi Chen, Manabu Maeda, Agnieszka Kruzynska-Frejtag, Jian Q. Feng, and Simon J. Conway periostin Null Mice Exhibit Dwarfism, Incisor Enamel Defects, and an Early-Onset Periodontal Disease-Like Phenotype Mol. Cell. Biol. 2005 25: 11131-11144 |
| 14. |
Yang W, Lu Y, Kalajzic I, Guo D, Harris MA, Gluhak-Heinrich J, Kotha S, Bonewald LF, Feng JQ, Rowe DW, Turner CH, Robling AG, Harris SE. Dentin Matrix Protein 1 Gene Cis-Regulation: Use in Osteocytes to Characterize Local Responses to Mechanical Loading In Vitro and In Vivo J Biol Chem. 280(21):20680-90, 2005 |
| 15. |
Ye, L, Mishina, Y, Chen, D, Huang, H, Dallas, S., Dallas, M., Y., Kunieda, T, Tsutsui, T., Bonewald, LF, and Feng JQ Dentin Matrix Protein 1 (Dmp1) Deficient Mice Display Severe Defects in Cartilage Formation Responsible for a Chondrodysplasia-like Phenotype J Biol Chem. 280(7):6197-203. 2005 |
| 16. |
Ye, L., MacDougall, M., Zhang, S., Xie, Y., Zhang, J.,Li, Z., Lu, Y., Mishina, Y. and Feng JQ Deletion of Dentin Matrix Protein-1 Leads to a Partial Failure of Maturation of Predentin into Dentin, Hypomineralization and Expanded Calvities of Pulp and Root Canal During Postnatal Tooth Development J Biol Chem. 2004 May 30;279(18):19141-8. |
| 17. |
Yang W, Kalajzic I, Lu Y, Guo D, Harris MA, Gluhak-Heinrich J, Bonewald LF, Feng JQ, Rowe DW, Harris SE. In vitro and in vivo study on osteocyte-specific mechanical signaling pathways J Musculoskelet Neuronal Interact. 2004 4:386-7. |
| 18. |
Wei Zheng, Yixia Xie, Gang Li, Juan Kong, Feng JQ, and Yan Chun Li Critical role of calbindin-D28k in calcium homeostasis revealed by mice lacking both vitamin D receptor and calbindin-D28k J. Biol. Chem . 279: 52406 – 52413, 2004 |
| 19. |
Jiwang Zhang, Chao Niu, Haiyang Huang, Ling Ye, Xi He, Weigang Tong, Jason Ross, Jeff Haug, Teri Johnson, Feng JQ, Stephen Harris, Leanne Wiedemann, Yuji Mishina, and Linheng Li, Identification of the Hematopoietic Stem Cell Niche and Control of the Niche Size Nature 425:836-841, 2003 |
| 20. |
Feng JQ, H. Huang, Y. Lu, L. Ye, Y. Xie, T. W. Tsutsui, T. Kunieda, T. Castranio, G. Scott, L. B. Bonewald and Y. Mishina Dmp1 is specifically expressed in mineralized tissues. Journal of Dental Research, 82: 776-780, 2003 |
| 21. |
Feng JQ, L Xing, J Zhang, M Zhao, D Horn, J Chan, BF Boyce, SE. Harris, GR. Mundy, and D Chen NF-kB specifically activates BMP-2 gene expression in growth plate chondrocytes in vivo and in a chondrocyte cell line in vitro. J Biol Chem 278:29130-29135, 2003 |
| 22. |
Feng JQ, Zhang, J, Tan, X, Lu, Y, Guo, D, Harris, S. E. Identification of cis-DNA regions controlling Bmp4 expression during tooth morphogenesis in vivo. J Dent Res 81, 6-10, 2002. |
| 23. |
Feng JQ, J. Zhang, A. Dallas, Y. Lu, S. Chen, X. Tan, M. Owen, S.E. Harris, M. MacDougall. Dentin Matrix Protein-1 Gene, a Target Molecule of Cbfa 1 in Bone, Dentin Matrix Protein-1, a Target Molecule for Cbfa 1 in Bone, is a Unique Bone Marker gene. Journal of Bone and Mineral Research 17:1822-1831, 2002 |
| 24. |
Zhang, J., Tan, X., Contag, C.H., Lu, Y., Guo, D., Harris, S.E., and Feng JQ. Dissection of Promoter Control Modules That Direct Bmp4 Expression in the Epithelium-Derived Components of Hair Follicles. BBRC 293: 1412-1419, 2002 |
| 25. |
Feng JQ., Xianghong Luan, John Wallace, Dai Jing, Ashuk B. Kulkuni, Rena N. D'Souza, Christina A, Kozak and MacDougall M. Genomic organization, chromosomal mapping and promoter analysis of mouse dentin sialophosphoprotein(Dspp) gene which codes for both dentin sialoprotein and dentin phosphoprotein J Biol Chem 273:9457-9464 1998 |
| 26. |
Feng JQ, Chen D, Ghosh-Choudhury N, Mundy GR and Harris SE Bone morphogenetic protein 2 transcripts in rapidly developing deer antler tissue contain an extended 5' non-coding region arising from a distal promoter. Biochim Biophys Acta 1350: 47-52 1997 |
| 27. |
Feng JQ, Chen D, Cooney A, Tsai MJ, Harris MA, Dallas SJ, Tsai SY, Feng M, Mundy GR, Harris SE The mouse bone morphogenetic protein 4 gene: Analysis of promoter utilization in fetal rat calvarial osteoblasts. J Biol Chem 270:28364-28373 1995 |
| 28. |
Feng JQ, Chen D, Esparza J, Harris MA, Mundy GR, Harris SE Deer antler tissue contains two types of bone morphogenetic protein 4 mRNA transcripts. Biochim Biophys Acta 1263:163-168 1995 |
| 29. |
Feng JQ, Harris MA, Ghosh-Choudhury N, Mundy GR, Harris SE: Structure and sequence of mouse bone morphogenetic protein 2: Comparison of the structures and promoter regions of BMP2 and BMP4 genes. Biochim Biophys Acta 1218:221-224 1994 |
| Feng JQ, and Clark NB. Renal responses to parathyroid hormone in young chickens. Am J Physiol 267:R295-R302 1994 |
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